Transcatheter Arterial Embolization to Treat Hip Osteoarthritis

A Pilot Case Series

Authors

DOI:

https://doi.org/10.59667/sjoranm.v27i1.28

Keywords:

osteoarthritis, hip, pain, embolization

Abstract

Chronic hip pain due to osteoarthritis (OA) is a source of disability in older adults. This prospective, single-center pilot case series, conducted under IRB approval, describes hip transcatheter arterial embolization (TAE) in four patients with persistent OA-related hip pain despite conservative treatment. Embolization was guided by angiographic blush and the feasibility of selective catheterization. Three arterial contributors were embolized in Case 1, the lateral circumflex femoral artery alone in Cases 2 and 3, and the lateral and medial circumflex femoral arteries in Case 4. Pain was assessed using the 0–10 Visual Analog Scale (VAS) at baseline and at 1, 3, and 6 months. At six months, all four patients had at least a 50% reduction in VAS score, with the mean decreasing from 9.75 to 1.75. No ischemic complications were reported during the six-month follow-up. These uncontrolled observations suggest a potential role for hip TAE in selected patients; they do not establish efficacy or safety. Larger controlled studies with longer follow-up are needed.

References

1. Murphy NJ, Eyles JP, Hunter DJ. Hip osteoarthritis: etiopathogenesis and implications for management. Adv Ther. 2016;33(11):1921-1946. https://doi.org/10.1007/s12325-016-0409-3

2. Murphy LB, Helmick CG, Schwartz TA, et al. One in four people may develop symptomatic hip osteoarthritis in his or her lifetime. Osteoarthritis Cartilage. 2010;18(11):1372-1379. https://doi.org/10.1016/j.joca.2010.08.005

3. Yao Q, Wu X, Tao C, et al. Osteoarthritis: pathogenic signaling pathways and therapeutic targets. Signal Transduct Target Ther. 2023;8(1):56. Published 2023 Feb 3. https://doi.org/10.1038/s41392-023-01330-w

4. Loeser RF, Goldring SR, Scanzello CR, Goldring MB. Osteoarthritis: a disease of the joint as an organ. Arthritis Rheum. 2012;64(6):1697-1707. https://doi.org/10.1002/art.34453

5. Katz JN, Arant KR, Loeser RF. Diagnosis and treatment of hip and knee osteoarthritis: a review. JAMA. 2021;325(6):568-578. https://doi.org/10.1001/jama.2020.22171

6. Clynes MA, Jameson KA, Edwards MH, Cooper C, Dennison EM. Impact of osteoarthritis on activities of daily living: does joint site matter? Aging Clin Exp Res. 2019;31(8):1049-1056. https://doi.org/10.1007/s40520-019-01163-0

7. Nicholas E, Cheng J, Moley PJ. Non-operative treatment options for osteoarthritis in the hip. HSS J. 2023;19(4):486-493. https://doi.org/10.1177/15563316231204437

8. Femia M, Valenti Pittino C, Fumarola EM, et al. Genicular Artery Embolization: A New Tool for the Management of Refractory Osteoarthritis-Related Knee Pain. J Pers Med. 2024;14(7):686. Published 2024 Jun 26. https://doi.org/10.3390/jpm14070686

9. Ferguson R, Prieto-Alhambra D, Peat G, et al. Influence of pre-existing multimorbidity on receiving a hip arthroplasty: cohort study of 28 025 elderly subjects from UK primary care. BMJ Open. 2021;11(9):e046713. https://doi.org/10.1136/bmjopen-2020-046713

10. Okuno Y, Korchi AM, Shinjo T, Kato S. Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis. Cardiovasc Intervent Radiol. 2015;38(2):336-343. https://doi.org/10.1007/s00270-014-0944-8

11. Okuno Y, Iwamoto W, Matsumura N, et al. Clinical outcomes of transcatheter arterial embolization for adhesive capsulitis resistant to conservative treatment. J Vasc Interv Radiol. 2017;28(2):161-167.e1. https://doi.org/10.1016/j.jvir.2016.09.028

12. Correa MP, Puton RC, Saleh JN, et al. Short-term follow-up of embolization of hip synovitis. CVIR Endovasc. 2020;3(1):35. https://doi.org/10.1186/s42155-020-00126-1

13. Sajan A, Epelboym Y, Martínez AF, Little M, Talaie R, Isaacson A. Transarterial embolization for musculoskeletal pain management: AJR Expert Panel narrative review. AJR Am J Roentgenol. 2025;224(2):e2431626. https://doi.org/10.2214/AJR.24.31626

14. Wang B, Liang KW, Chen CH, Wang CK. Transcatheter arterial embolization for alleviating chronic musculoskeletal pain and improving physical function: a narrative review. Diagnostics (Basel). 2022;13(1):134. https://doi.org/10.3390/diagnostics13010134

15. Correa MP, Motta-Leal-Filho JM, Junior EB, et al. 6-Month Follow-up of Lateral Femoral Circumflex Artery Embolization to Control Pain Related to Hip Osteoarthritis and Greater Trochanteric Pain Syndrome. Cardiovasc Intervent Radiol. 2022;45(11):1710-1715. https://doi.org/10.1007/s00270-022-03253-5

16. Bagla S, Piechowiak R, Sajan A, Orlando J, Hartman T, Isaacson A. Multicenter randomized sham-controlled study of genicular artery embolization for knee pain secondary to osteoarthritis. J Vasc Interv Radiol. 2022;33(1):2-10.e2. https://doi.org/10.1016/j.jvir.2021.09.019

17. Okuno Y, Matsumura N, Oguro S. Transcatheter arterial embolization using imipenem/cilastatin sodium for tendinopathy and enthesopathy refractory to nonsurgical management. J Vasc Interv Radiol. 2013;24(6):787-792. https://doi.org/10.1016/j.jvir.2013.02.033

18. Heller GZ, Manuguerra M, Chow R. How to analyze the visual analogue scale: myths, truths and clinical relevance. Scand J Pain. 2016;13:67-75. https://doi.org/10.1016/j.sjpain.2016.06.012

Published

2026-01-30

Data Availability Statement

Research data are not made available to the public, but upon request by the editors, a blinded version without identifying patient health information may be provided.

Issue

Section

Case reports

How to Cite

Krishnamurthy, P., Konduru, N., & Rao, S. (2026). Transcatheter Arterial Embolization to Treat Hip Osteoarthritis: A Pilot Case Series. Swiss Journal of Radiology and Nuclear Medicine, 27(1), 74-82. https://doi.org/10.59667/sjoranm.v27i1.28

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