MRI regional strain analysis in patients with hypertrophic cardiomyopathy
DOI:
https://doi.org/10.59667/sjoranm.v20i1.18Keywords:
Hypertrophic cardiomyopathy, regional strain analysis, cardiac MRIAbstract
Purpose
To describe regional left ventricular myocardial deformation in patients with hypertrophic cardiomyopathy (HCM) using cardiac MRI.
Materials and Methods
Twenty-five patients with HCM and 25 control participants with normal cardiac MRI underwent 1.5-T imaging. Regional radial, circumferential and longitudinal deformation was assessed using feature tracking. For this correction, the published aggregate results were reviewed descriptively. Individual-level data were unavailable for independent reanalysis.
Results
The tabulated mean radial strain was 20.10% in hypertrophied HCM segments, 27.71% in HCM segments of apparently normal thickness and 30.56% in controls. Corresponding circumferential values were −11.38%, −14.96% and −17.22%; longitudinal values were −5.95%, −12.21% and −13.59%. The tables reported 400 HCM segments for radial and circumferential analysis and 392 for longitudinal analysis. Statistical significance and previously reported AI classification performance could not be independently verified.
Conclusion
The reported aggregate values suggest reduced deformation magnitude in hypertrophied segments, with intermediate values in HCM segments of apparently normal thickness. These observations are descriptive and hypothesis-generating. They do not establish diagnostic accuracy, treatment-monitoring benefit or performance in genotype-positive individuals without hypertrophy.
References
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Data Availability Statement
The original article stated that data were available from the corresponding author upon reasonable request. Individual-level data and analysis code were not available to the editors during this correction. The revision is based on the submitted manuscript, submitted tables and published article.
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Copyright (c) 2025 Esraa Maher, Magdi Khalil, Mona Taher, Sameh Khalil
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