The Contribution of [18F] FDG PET/CT in the Diagnosis of Prosthetic Valve Infective Endocarditis

A Case Report

Authors

DOI:

https://doi.org/10.59667/sjoranm.v24i1.20

Abstract

Introduction: Infective endocarditis is a potentially life-threatening disease that requires rapid and accurate diagnosis. Recently, [18F] FDG PET/CT has been incorporated as a new major criterion for the diagnosis of infective endocarditis.

Case Report: This report describes a 54-year-old female patient who underwent mitral valve replacement in 2018 for symptomatic severe mitral stenosis with atrial fibrillation. She presented with infectious symptoms on clinical examination. Following transthoracic and transesophageal echocardiography, the differential diagnosis included prosthetic valve infective endocarditis versus mechanical prosthesis thrombosis. [18F] FDG PET/CT ultimately confirmed the diagnosis of prosthetic valve infective endocarditis.

Conclusion: This case highlights the significant advantages of [18F] FDG PET/CT in the diagnostic evaluation of patients with suspected prosthetic valve infective endocarditis, particularly when conventional echocardiographic examinations are inconclusive.

Keywords: Endocarditis, Fluorodeoxyglucose F18, Positron Emission Tomography

Author Biographies

  • Zakaria Ouassafrar, Nuclear Medicine Department, Ibn Rochd University Hospital Center, Casablanca, Morocco

    Professeur assisstant (Service de médecine nucléaire)

  • Abdel Amide Gbadamassi, Nuclear Medicine Department, Ibn Rochd University Hospital Center, Casablanca, Morocco

    MD | Nuclear Medicine Resident | MSc in Medical Biophysics | Project Management and Monitoring & Evaluation Administrator

  • Amal Guensi, Nuclear Medicine Department, Ibn Rochd University Hospital Center, Casablanca, Morocco

    Head of the Nuclear Medicine Department at CHU Ibn Rochd (Nuclear Medicine Department, Ibn Rochd University Hospital Center) in Casablanca, and affiliated with Hassan II University / Faculty of Medicine and Pharmacy of Casablanca (FMPC)

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Published

2025-10-31

How to Cite

The Contribution of [18F] FDG PET/CT in the Diagnosis of Prosthetic Valve Infective Endocarditis: A Case Report. (2025). Swiss Journal of Radiology and Nuclear Medicine, 24(1), 23-27. https://doi.org/10.59667/sjoranm.v24i1.20

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