Vol. 7 No. 1 (2024): Vol. 07 No. 1 (2024)

This work provides an overview of the effectiveness of bone scintigraphy and its role in diagnosing various benign conditions in the Nuclear Medicine Department of the University Hospital of Fez. It analyzes the criteria for selecting scintigraphy as a diagnostic tool and outlines the principles, key features, and protocols involved. These details support clinicians in confirming their diagnostic reasoning when evaluating musculoskeletal lesions or bone abnormalities, guiding their choice of imaging modalities. Fibrodysplasia ossificans progressiva (FOP) is an extremely uncommon autosomal dominant condition marked by abnormalities in the big toes and the gradual development of extra-skeletal bone in specific anatomical formations.

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Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare autosomal dominant condition characterized by malformations of the big toes and progressive extra-skeletal ossifications in distinct anatomical patterns. In FOP, heterotopic ossification (HO) occurs episodically, resulting from spontaneous flare-ups or trauma, leading to cumulative disability. Bone scintigraphy with 99mTc-MDP combined with SPECT-CT is instrumental in early detection, diagnosis, staging, and disease monitoring by highlighting HO sites.